What is graft-versus-host disease?
Graft-versus-host disease is a complication that can occur following an allogeneic hematopoietic stem cell transplantation.
Types
There are two distinct forms of graft-versus-host disease (GvHD), acute and chronic GvHD.
Causes and symptoms
Graft-versus-host disease can occur following allogeneic hematopoietic stem cell transplantation when the donor cells identify the recipient's tissue as foreign and attack it. Symptoms can range from mild to severe and, in some cases, life-threatening.
Latest insights & stories
Hear from others about their experience of living with graft-versus-host disease, and the latest insights from experts in the field, from diagnosis to treatment and beyond.
How can patients become involved in clinical trials, and why is it important to capture their experience?
Know GvHD was pleased to speak to Mohamad Mohty, Hôpital Saint-Antoine and Sorbonne University, Paris, FR. We asked, How can patients become involved in clinical trials, and why is it important to capture their experience?
How do physicians decide which treatment to use in patients with GvHD?
Know GvHD was pleased to speak to Hildegard Greinix, Medical University of Vienna, Austria. We asked, How do physicians decide which treatment to use in patients with graft-versus-host disease (GvHD)?
What is steroid-refractory GvHD, and how is it treated?
Know GvHD was pleased to speak to Hildegard Greinix, Medical University of Vienna, Austria. We asked, What is steroid-refractory graft-versus-host disease (GvHD), and how is it treated?
Educational resources
We aim to share resources in a variety of formats to help support someone diagnosed with graft-versus-host disease, as well as tools and content to be shared to raise awareness of Graft-versus-host disease.
What is ECP?
This graphic defines extracorporeal photopheresis (ECP) and explains it is a procedure to treat GvHD often when other treatments have not worked.
What steps are involved in ECP?
An overview of the steps in ECP, including drawing blood from the patient, treating it with ultraviolet light, and returning it to the patient.
What are the side effects of ECP?
A summary of the common side effects of ECP, which can include nausea, light sensitivity, and dizziness.
About us
Know GvHD is dedicated to improving understanding of GvHD worldwide through education, community collaboration, and raising awareness of available resources.
By partnering with patient advocates, societies, and our GvHD Hub Steering Committee, we ensure our content reflects the patient voice and healthcare professional insights, making it as impactful and supportive as possible.
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