Know GvHD | Scientific Education Support

Know GvHD is a global education and awareness initiative that provides patients and caregivers with the information, resources, and support they need to deal with graft-versus-host disease

Understanding GvHD

Find out more about graft-versus-host disease below.

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What is graft-versus-host disease?

Graft-versus-host disease is a complication that can occur following an allogeneic hematopoietic stem cell transplantation.

Types

There are two distinct forms of graft-versus-host disease (GvHD), acute and chronic GvHD.

Causes and symptoms

Graft-versus-host disease can occur following allogeneic hematopoietic stem cell transplantation when the donor cells identify the recipient's tissue as foreign and attack it. Symptoms can range from mild to severe and, in some cases, life-threatening.

Latest insights & stories

Hear from others about their experience of living with graft-versus-host disease, and the latest insights from experts in the field, from diagnosis to treatment and beyond.

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Can you describe your treatment journey as a patient with GvHD?

Know GvHD was pleased to speak to Wilfred Emmanuel-Jones, UK, about his treatment journey as a patient with GvHD.

What advice would you give to someone who is about to start treatment for GvHD?

Know GvHD was pleased to speak to Joanne Stobart, UK. We asked, What advice would you give to someone who is about to start treatment for GvHD?

Have you experienced other complications due to treatments you received for GvHD?

Know GvHD was pleased to speak to Steven Jackson, US. We asked, Have you experienced other complications due to treatments you received for GvHD?

Educational resources

We aim to share resources in a variety of formats to help support someone diagnosed with graft-versus-host disease, as well as tools and content to be shared to raise awareness of Graft-versus-host disease.

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What is ECP?

This graphic defines extracorporeal photopheresis (ECP) and explains it is a procedure to treat GvHD often when other treatments have not worked.

What steps are involved in ECP?

An overview of the steps in ECP, including drawing blood from the patient, treating it with ultraviolet light, and returning it to the patient.

What are the side effects of ECP?

A summary of the common side effects of ECP, which can include nausea, light sensitivity, and dizziness.

About us

Know GvHD is dedicated to improving understanding of GvHD worldwide through education, community collaboration, and raising awareness of available resources.

By partnering with patient advocates, societies, and our GvHD Hub Steering Committee, we ensure our content reflects the patient voice and healthcare professional insights, making it as impactful and supportive as possible.

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